Publications

Selected Publications

Shared structural features of Miro binding control mitochondrial homeostasis. 

Christian Covill-Cooke , Brian Kwizera, Guillermo López-Doménech, Caleb OD Thompson, Ngaam J Cheung, Ema Cerezo, Martin Peterka, Josef T Kittler, and Benoît Kornmann https://doi.org/10.1038/s44318-024-00028-1

METALIC reveals interorganelle lipid flux in live cells by enzymatic mass tagging. 

Arun T. John Peter, Carmeina Petrungaro, Matthias Peter, Benoît Kornmann Nat Cell Biol. 2022 Jun 2 , doi:https://doi.org/10.1038/s41556-022-00917-9 

Rewiring phospholipid biosynthesis reveals robustness in membrane homeostasis and uncovers lipid regulatory players

Arun T. John Peter, Sabine N. S. van Schie, Ngaam J. Cheung, Agnès H. Michel, Matthias Peter, Benoît Kornmann, EMBO J, e109998  https://www.embopress.org/doi/full/10.15252/embj.2021109998

Exploiting homologous recombination increases SATAY efficiency for loss- and gain-of-function screening

Agnès H. Michel, Sabine van Schie, Andreas Mosbach, Gabriel Scalliet, Benoît Kornmann, BiorXiv doi: https://doi.org/10.1101/866483 

Miro-dependent mitochondrial pool of CENP-F and its farnesylated C-terminal domain are dispensable for normal development in mice

Martin Peterka, Benoît Kornmann (2019) PLoS Genetics  accepted bioRxiv. doi: https://doi.org/10.1101/415315 

Mechanical force induces mitochondrial fission

Sebastian CJ Helle*, Qian Feng*, Mathias J Aebersold, Luca Hirt, Raphael R Grüter, Afshin Vahid, Andrea Sirianni, Serge Mostowy, Jess G Snedeker, Anđela Šarić, Timon Idema, Tomaso Zambelli, Benoît Kornmann (2017) eLife. Nov 9;6. pii: e30292. doi: 10.7554/eLife.30292. 
*equal contribution

Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondria contact sites.

Arun T. John Peter, Beatrice Herrmann, Diana Antunes, Doron Rapaport, Kai S.Dimmer, Benoît Kornmann(2017) J Cell Biol. 216(10):3219-3229

CENP-F couples cargo to growing and shortening microtubule ends

Gil Kanfer*, Martin Peterka*, Vladimir K. Arzhanik*, Alexei L. Drobyshev, Fazly I. Ataullakhanov, Vladimir A. Volkov, Benoît Kornmann (2017) Mol Biol Cell. 2017 28(18):2400-2409
Link *equal contribution

Functional mapping of yeast genomes by saturated transposition

Agnès H. Michel, Riko Hatakeyama, Philipp Kimmig, Meret Arter, Matthias Peter, Joao Matos, Claudio De Virgilio, Benoît Kornmann (2017) eLife 2017;10.7554/eLife.23570

ER-mitochondrial Junctions can be Bypassed by Dominant Mutations in the Endosomal Protein Vps13.

Lang A, John Peter AT, Walter P, Kornmann, B (2015) J. Cell Biol. 210(6):883-8900

Mitotic redistribution of the mitochondrial network by Miro and Cenp-F

Kanfer G, Courthéoux T, Peterka M, Meier S, Soste M, Melnik A, Reis K, Aspenström P, Peter M, Picotti P & Kornmann B (2015) Nat. Commun. Aug 11;6:8015

Organization and Function of Membrane Contact Sites

Helle SCJ*, Kanfer G*, Kolar K*, Lang A*, Michel AH*, Kornmann B (2013) Biochim Biophys Acta, 1833(11):2526-41 

The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections.

Kornmann B, Osman C and Walter P (2011). Proc Natl Acad Sci USA, 108, 14151-6

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen.

Kornmann B, Currie E, Collins S R, Schuldiner M, Nunnari J, Weissman J S and Walter P (2009). Science, 325, 477-81

All Publications

METALIC reveals interorganelle lipid flux in live cells by enzymatic mass tagging.

John Peter AT, Petrungaro C, Peter M, Kornmann B. Nat Cell Biol. 2022 Jun 2. doi: 10.1038/s41556-022-00917-9. Online ahead of print. PMID: 35654841


SAturated Transposon Analysis in Yeast (SATAY) for Deep Functional Mapping of Yeast Genomes.

Michel AH, Kornmann B. Methods Mol Biol. 2022;2477:349-379. doi: 10.1007/978-1-0716-2257-5_20. PMID: 35524127


Mitochondria transplantation between living cells.

Gäbelein CG, Feng Q, Sarajlic E, Zambelli T, Guillaume-Gentil O, Kornmann B, Vorholt JA. PLoS Biol. 2022 Mar 23;20(3):e3001576. doi: 10.1371/journal.pbio.3001576. eCollection 2022 Mar. PMID: 35320264 Free PMC article.


Rewiring phospholipid biosynthesis reveals resilience to membrane perturbations and uncovers regulators of lipid homeostasis.

John Peter AT, van Schie SNS, Cheung NJ, Michel AH, Peter M, Kornmann B. EMBO J. 2022 Apr 4;41(7):e109998. doi: 10.15252/embj.2021109998. Epub 2022 Feb 21. PMID: 35188676 Free PMC article.


SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways.

Serbyn N, Bagdiul I, Noireterre A, Michel AH, Suhandynata RT, Zhou H, Kornmann B, Stutz F. Cell Rep. 2021 Nov 23;37(8):110034. doi: 10.1016/j.celrep.2021.110034. PMID: 34818558 Free article.


Editorial: Coupling and Uncoupling: Dynamic Control of Membrane Contacts.

Zhang D, Saheki Y, Hu J, Kornmann B. Front Cell Dev Biol. 2021 Aug 24;9:721546. doi: 10.3389/fcell.2021.721546. eCollection 2021. PMID: 34504844 Free PMC article. No abstract available.


Leri: A web-server for identifying protein functional networks from evolutionary couplings.

Cheung NJ, John Peter AT, Kornmann B. Comput Struct Biotechnol J. 2021 Jun 6;19:3556-3563. doi: 10.1016/j.csbj.2021.06.002. eCollection 2021. PMID: 34257835 Free PMC article.


A mechanism to PLAse the eye.

Covill-Cooke C, Kornmann B. Dev Cell. 2021 Jun 7;56(11):1560-1561. doi: 10.1016/j.devcel.2021.05.009. PMID: 34102103


Indole-3-acetic acid is a physiological inhibitor of TORC1 in yeast.

Nicastro R, Raucci S, Michel AH, Stumpe M, Garcia Osuna GM, Jaquenoud M, Kornmann B, De Virgilio C. PLoS Genet. 2021 Mar 9;17(3):e1009414. doi: 10.1371/journal.pgen.1009414. eCollection 2021 Mar. PMID: 33690632 Free PMC article.


ER-mitochondria contacts promote mitochondrial-derived compartment biogenesis.

English AM, Schuler MH, Xiao T, Kornmann B, Shaw JM, Hughes AL. J Cell Biol. 2020 Dec 7;219(12):e202002144. doi: 10.1083/jcb.202002144. PMID: 33090183 Free PMC article.


ESCRT-III and ER-PM contacts maintain lipid homeostasis. 

Jorgensen JR, Tei R, Baskin JM, Michel AH, Kornmann B, Emr SD. Mol Biol Cell. 2020 Jun 1;31(12):1302-1313. doi: 10.1091/mbc.E20-01-0061. Epub 2020 Apr 8. PMID: 32267208 


The endoplasmic reticulum-mitochondria encounter structure: coordinating lipid metabolism across membranes. 

Kornmann B. Biol Chem. 2020 Mar 3:/j/bchm.ahead-of-print/hsz-2020-0102/hsz-2020-0102.xml. doi: 10.1515/hsz-2020-0102. Online ahead of print. PMID: 32049644 Review. 

 

Liquid but not contactless. 

Kornmann B, Weis K. Science. 2020 Jan 31;367(6477):507-508. doi: 10.1126/science.aba3771. PMID: 32001641 No abstract available. 


The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast. 

Serbyn N, Noireterre A, Bagdiul I, Plank M, Michel AH, Loewith R, Kornmann B, Stutz F. Mol Cell. 2020 Mar 5;77(5):1066-1079.e9. doi: 10.1016/j.molcel.2019.12.007. Epub 2020 Jan 2. PMID: 31902667 


Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae. 

Haribowo AG, Hannich JT, Michel AH, Megyeri M, Schuldiner M, Kornmann B, Riezman H. Mol Biol Cell. 2019 Oct 15;30(22):2814-2826. doi: 10.1091/mbc.E19-07-0364. Epub 2019 Sep 11. PMID: 31509475 Free PMC article.  


A Toolbox for Organelle Mechanobiology Research-Current Needs and Challenges. 

Feng Q, Lee SS, Kornmann B. Micromachines (Basel). 2019 Aug 16;10(8):538. doi: 10.3390/mi10080538. PMID: 31426349 Free PMC article. 


Coming Together to Define Membrane Contact Sites 

Scorrano L, De Matteis MA, Emr S, et al. Nat Commun. 2019;10(1):1287. Published 2019 Mar 20. doi:10.1038/s41467-019-09253-3 


Miro-dependent Mitochondrial Pool of CENP-F and Its Farnesylated C-terminal Domain Are Dispensable for Normal Development in Mice 

Peterka M, Kornmann B. PLoS Genet. 2019;15(3):e1008050. Published 2019 Mar 11. doi:10.1371/journal.pgen.1008050


Lipid exchange at ER-mitochondria contact sites: a puzzle falling into place with quite a few pieces missing.

Petrungaro C, Kornmann B.

Curr Opin Cell Biol. 2018 Dec 13;57:71-76. doi: 10.1016/j.ceb.2018.11.005. Review.


Mechanical forces on cellular organelles.

Feng Q, Kornmann B.

J Cell Sci. 2018 Oct 29;131(21). pii: jcs218479. doi: 10.1242/jcs.218479. Review.


Organelle morphogenesis, targeting, and distribution.

Carlton JG, Kornmann B.

Mol Biol Cell. 2018 Mar 15;29(6):692-693. doi: 10.1091/mbc.E17-11-0681. No abstract available. 


Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES.

Kawano S, Tamura Y, Kojima R, Bala S, Asai E, Michel AH, Kornmann B, Riezman I, Riezman H, Sakae Y, Okamoto Y, Endo T.

J Cell Biol. 2018 Mar 5;217(3):959-974. doi: 10.1083/jcb.201704119. Epub 2017 Dec 26.


Mechanical force induces mitochondrial fission.

Helle SCJ, Feng Q, Aebersold MJ, Hirt L, Grüter RR, Vahid A, Sirianni A, Mostowy S, Snedeker JG, Šarić A, Idema T, Zambelli T, Kornmann B.

Elife. 2017 Nov 9;6. pii: e30292. doi: 10.7554/eLife.30292.


Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondria contact sites.

John Peter AT, Herrmann B, Antunes D, Rapaport D, Dimmer KS, Kornmann B.

J Cell Biol. 2017 Oct 2;216(10):3219-3229. doi: 10.1083/jcb.201610055. Epub 2017 Sep 1.


Peptide-Membrane Interaction between Targeting and Lysis.

Stutz K, Müller AT, Hiss JA, Schneider P, Blatter M, Pfeiffer B, Posselt G, Kanfer G, Kornmann B, Wrede P, Altmann KH, Wessler S, Schneider G.

ACS Chem Biol. 2017 Sep 15;12(9):2254-2259. doi: 10.1021/acschembio.7b00504. Epub 2017 Aug 8.


CENP-F couples cargo to growing and shortening microtubule ends.

Kanfer G, Peterka M, Arzhanik VK, Drobyshev AL, Ataullakhanov FI, Volkov VA, Kornmann B.

Mol Biol Cell. 2017 Sep 1;28(18):2400-2409. doi: 10.1091/mbc.E16-11-0756. Epub 2017 Jul 12.


Membrane contact sites.

Kornmann B, Ungermann C.

Biochim Biophys Acta Mol Cell Res. 2017 Sep;1864(9):1435-1438. doi: 10.1016/j.bbamcr.2017.06.014. Epub 2017 Jun 23. No abstract available. 


Functional mapping of yeast genomes by saturated transposition.

Michel AH, Hatakeyama R, Kimmig P, Arter M, Peter M, Matos J, De Virgilio C, Kornmann B.

Elife. 2017 May 8;6. pii: e23570. doi: 10.7554/eLife.23570.


Eighth International Chorea-Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points.

Pappas SS, Bonifacino J, Danek A, Dauer WT, De M, De Franceschi L, DiPaolo G, Fuller R, Haucke V, Hermann A, Kornmann B, Landwehrmeyer B, Levin J, Neiman AM, Rudnicki DD, Sibon O, Velayos-Baeza A, Vonk JJ, Walker RH, Weisman LS, Albin RL.

Tremor Other Hyperkinet Mov (N Y). 2017 Feb 15;7:428. doi: 10.7916/D8XD127W. eCollection 2017.


High resolution microscopy reveals an unusual architecture of the Plasmodium berghei endoplasmic reticulum.

Kaiser G, De Niz M, Zuber B, Burda PC, Kornmann B, Heussler VT, Stanway RR.

Mol Microbiol. 2016 Dec;102(5):775-791. doi: 10.1111/mmi.13490. Epub 2016 Sep 26.


Dynamics of the mitochondrial network during mitosis.

Kanfer G, Kornmann B.

Biochem Soc Trans. 2016 Apr 15;44(2):510-6. doi: 10.1042/BST20150274. Review.


ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13.

Lang AB, John Peter AT, Walter P, Kornmann B.

J Cell Biol. 2015 Sep 14;210(6):883-90. doi: 10.1083/jcb.201502105.


Mitotic redistribution of the mitochondrial network by Miro and Cenp-F.

Kanfer G, Courthéoux T, Peterka M, Meier S, Soste M, Melnik A, Reis K, Aspenström P, Peter M, Picotti P, Kornmann B.

Nat Commun. 2015 Aug 11;6:8015. doi: 10.1038/ncomms9015.


ER-mitochondria contact sites in yeast: beyond the myths of ERMES.

Lang A, John Peter AT, Kornmann B.

Curr Opin Cell Biol. 2015 Aug;35:7-12. doi: 10.1016/j.ceb.2015.03.002. Epub 2015 Mar 30. Review.


Quality control in mitochondria: use it, break it, fix it, trash it.

Kornmann B.

F1000Prime Rep. 2014 Mar 3;6:15. doi: 10.12703/P6-15. eCollection 2014. Review.


The molecular hug between the ER and the mitochondria.

Kornmann B.

Curr Opin Cell Biol. 2013 Aug;25(4):443-8. doi: 10.1016/j.ceb.2013.02.010. Epub 2013 Mar 13. Review.


Organization and function of membrane contact sites.

Helle SC, Kanfer G, Kolar K, Lang A, Michel AH, Kornmann B.

Biochim Biophys Acta. 2013 Nov;1833(11):2526-41. doi: 10.1016/j.bbamcr.2013.01.028. Epub 2013 Feb 1. Review.


Lipids as organizers of cell membranes.

Kornmann B, Roux A.

EMBO Rep. 2012 Aug;13(8):667-9. doi: 10.1038/embor.2012.104. Epub 2012 Jul 13.


The ERMES complex and ER-mitochondria connections.

Michel AH, Kornmann B.

Biochem Soc Trans. 2012 Apr;40(2):445-50. doi: 10.1042/BST20110758. Review.


The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections.

Kornmann B, Osman C, Walter P.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14151-6. doi: 10.1073/pnas.1111314108. Epub 2011 Aug 8.


ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology.

Kornmann B, Walter P.

J Cell Sci. 2010 May 1;123(Pt 9):1389-93. doi: 10.1242/jcs.058636.


[ERMES, a multifunctional complex connecting endoplasmic reticulum and mitochondria].

Kornmann B.

Med Sci (Paris). 2010 Feb;26(2):145-6. doi: 10.1051/medsci/2010262145. French. No abstract available. 


REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis.

Le Martelot G, Claudel T, Gatfield D, Schaad O, Kornmann B, Lo Sasso G, Moschetta A, Schibler U.

PLoS Biol. 2009 Sep;7(9):e1000181. doi: 10.1371/journal.pbio.1000181. Epub 2009 Sep 1.

19721697 


An ER-mitochondria tethering complex revealed by a synthetic biology screen.

Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P.

Science. 2009 Jul 24;325(5939):477-81. doi: 10.1126/science.1175088. Epub 2009 Jun 25.

19556461 


Regulation of circadian gene expression in liver by systemic signals and hepatocyte oscillators.

Kornmann B, Schaad O, Reinke H, Saini C, Schibler U.

Cold Spring Harb Symp Quant Biol. 2007;72:319-30. doi: 10.1101/sqb.2007.72.041. Review.

18419289 


[The central circadian clock and peripheral clocks: decentralization and hierarchical control].

Kornmann B.

Med Sci (Paris). 2007 Apr;23(4):349-50. French. No abstract available. 

17433220 


System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock.

Kornmann B, Schaad O, Bujard H, Takahashi JS, Schibler U.

PLoS Biol. 2007 Feb;5(2):e34.

17298173 


Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing.

Michel AH, Kornmann B, Dubrana K, Shore D.

Genes Dev. 2005 May 15;19(10):1199-210.

15905408 


Circadian gene expression in cultured cells.

Nagoshi E, Brown SA, Dibner C, Kornmann B, Schibler U.

Methods Enzymol. 2005;393:543-57.

15817311 


Analysis of circadian liver gene expression by ADDER, a highly sensitive method for the display of differentially expressed mRNAs.

Kornmann B, Preitner N, Rifat D, Fleury-Olela F, Schibler U.

Nucleic Acids Res. 2001 Jun 1;29(11):E51-1.

11376163 


Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus.

Damiola F, Le Minh N, Preitner N, Kornmann B, Fleury-Olela F, Schibler U.

Genes Dev. 2000 Dec 1;14(23):2950-61.

11114885